Claire Wyart

The Wyart lab investigates how internal and external sensory cues are integrated to shape movements and posture during active locomotion. We discovered a novel sensory system in the vertebrate spinal cord. We show that sensory neurons contacting the cerebrospinal fluid (CSF) together with the Reissner fiber detect changes of CSF flow associated with curvature of the spine. These interoceptor neurons modulate the activity of spinal interneurons controlling locomotion and posture. The Wyart lab has investigated the role of this novel sensory system in postural control, morphogenesis of the spine and detection of pathogens during infections of the nervous system. We are now eager to decipher in the brain the motor circuits controlling basic exploration and its modulation based on inner states and external sensory cues.

Projects at ZENITH

• Inner States
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