Isaac BiancoIdentifying the neural circuits that link visual perception to action
The Bianco lab (UCL, London, UK) investigates how the brain links perception of visual cues to the selection and execution of actions by combining behavioural analyses, calcium imaging, optogenetics and modelling.
The Bianco lab wants to understand how animals make sense of their visual world to generate appropriate behaviour. We study how the brain perceives salient visual cues (for instance related to predators and prey), how visual perception is combined with internal state information to select appropriate actions, and how motor pattern generators orchestrate relevant behavioural programs. The lab combines behavioural assays, calcium imaging, optogenetics, anatomy and modelling to map the structure and function of visuomotor circuits that transform sensory information into action.
Publication 1: Antinucci P, Folgueira M, Bianco IH. A pretectal command system controls hunting behaviour. biorXiv preprint: doi.org/10.1101/637215.
Publication 2: Henriques PM, Rahman N, Jackson SE, Bianco IH. Nucleus Isthmi is required to sustain target pursuit during visually guided prey-catching. Current Biology (2019) 29:1771-1786. doi.org/10.1016/j.cub.2019.04.064.
Publication 3: Bianco IH and Engert F. Visuomotor transformations underlying hunting behavior in zebrafish. Current Biology (2015). 25:1-16.