The Del Bene lab is located at the Institut de la Vision in Paris. It investigates the complex interplay of molecules that regulate the formation of neural circuits, and how these circuits function together to produce behavior in response to visual stimuli.
Thanks to anatomical, molecular and functional studies and using cutting-edge tools, the teams of Dr. Del Bene aims at unravel neuronal circuits development at the cellular and molecular level, in order to better understand human ocular diseases as well as neurological disorders leading to inappropriate behaviors and whose etiologies are yet to be defined.
Publication 1: Di Donato V, De Santis F, Albadri S, Auer TO, Duroure K, Charpentier M, Concordet JP, Gebhardt C, Del Bene F: An Attractive Reelin Gradient Establishes Synaptic Lamination in the Vertebrate Visual System. Neuron 2018,Mar 7;97(5):1049-1062.e6. DOI: 10.1016/j.neuron.2018.01.030.
Publication 2: Dunn TW, Gebhardt C, Naumann EA, Riegler C, Ahrens MB, Engert F, Del Bene F. Neural Circuits Underlying Visually Evoked Escapes in Larval Zebrafish. Neuron. 2016 Feb 3;89(3):613-28. DOI: 10.1016/j.neuron.2015.12.021.
Publication 3: Gebhardt, C., Auer, T.O., Henriques, P.M., Rajan, G., Duroure, K., Bianco, I.H., Bene, F.D., 2019. An interhemispheric neural circuit allowing binocular integration in the optic tectum. Nat Commun 10, 1–12. DOI: 10.1038/s41467-019-13484-9