Vocalisation

Vocalisation
Identify circuits underlying communication in the smallest vertebrate brain

Danionella translucida, a transparent relative of zebrafish, has the smallest known vertebrate brain and sings under water. The goal of this project is to identify neural circuits underlying vocal-motor control and communication in Danionella.

A hallmark of social behavior is communication. BJ’s lab found that a freshwater Danionin closely related to zebrafish, Danionella translucida, communicates using acoustic signals. Danionella adults are among the smallest living adult vertebrates, thereby combining the size and transparency of zebrafish larvae with the behavioral complexity of an adult. The goal of this project is to identify neural circuits underlying vocal-motor control and communication, using a combination of single-cell sequencing, transgenic and optical techniques.

Publications

  • Publication 1: Schulze L, Henninger J, Kadobianskyi M, Chaigne T, Faustino AI, Hakiy N, Albadri S, Schuelke M, Maler L, Del Bene F, Judkewitz B: Transparent Danionella translucida as a genetically tractable vertebrate brain model, Nature Methods 2018, doi.org/10.1038/s41592-018-0144-6.

  • Publication 2: Kadobianskyi M, Schulze L, Schuelke M, Judkewitz B: Hybrid genome assembly and annotation of Danionella translucida, Scientific Data 2019, 6:156, http://doi.org/10.1038/s41597-019-0161-z.

  • Publication 3: Papadopoulos IN, Jouhanneau JS, Poulet JFA, Judkewitz B. Scattering compensation by focus scanning holographic aberration probing (F-SHARP), Nature Photonics 2017, 11:116-23 doi:10.1038/nphoton.2016.252